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Mr Daniel Leff, Male

Clinical senior lecturer and honorary consultant oncoplastic breast surgeon 4733638
Photo of Mr Daniel Leff Male


Daniel is currently a Reader in Breast Surgery working in the Departments of BioSurgery and Surgical Technology, the Hamlyn Centre for Robotic Surgery and the Cancer Research UK Centre at Imperial College London. He is an Honorary Consultant in Oncoplastic Breast Surgery working within the Breast Unit at Imperial College Healthcare NHS Trust. Daniel trained at several centres of excellence in breast cancer and reconstructive breast surgery including the Imperial Breast Unit, and the Royal Marsden NHS Foundation Trust. He was competitively selected for a National Training Fellowship (one of only nine such posts in the UK) and completed Advanced Oncoplastic Breast Surgery training at the St Andrews Centre for Plastic Surgery and Breast Unit in Chelmsford. He won the Ronald Raven Prize Travelling Fellowship to learn from International experts in Breast Cancer and Reconstructive Surgery at the MD Anderson Cancer Center, the forefront of cancer care in the USA. More recently he won the “Issac Gukas Medal” for outstanding achievement in Breast Surgery.

Daniel’s main interest is in the development of novel systems and technologies to improve the diagnosis or surgical management of breast cancer. He Co-lead investigator on the CRUK funded “REI-EXCISE” trial which seeks to validate a mass-spectrometry based intelligent knife or “iKnife” as an immediate margin detection system to improve the precision of breast conserving surgery, reduce re-operative intervention, and enhance quality of life. He leads a UK wide team working on a CRUK-EPSRC funded project “MAMMOBOT” to design a flexible growing ductoscopic robot for early breast cancer detection. Daniel Co-Chairs the “Precision Therapy” theme of Imperial’s CRUK Centre and represents cancer surgery for the Imperial ECMC. He has published over 100 scientific papers in peer-reviewed journals on subjects relating to the application of surgical technologies, sensing and robotics to improve cancer surgery. Daniel’s research has won national and international recognition, including the Hounsfield Prize, British Journal of Surgery Prize (ABS), Patey Prize (SARS), Sir Pat Forrest Award (BBG), Parasuraman Award, Athanasiou Medal (ABME), and the young scientist award at MICCAI. He has attracted funding from Industry (Waters Corp, Hitachi Medical Corp), the Academy of Medical Sciences and Wellcome Trust (AMS), Engineering and Physical Sciences Research Council (EPSRC), Association of Breast Surgery and Cancer Research UK (CRUK). He has delivered a number of key-note lectures around the world including “McGuire Lecture in Surgical Oncology”(Queens University, Kingston, Canada).

Special interests

  • Oncoplastic surgery
  • Diagnosis of breast diseases
  • Therapeutic mammoplasty
  • Sentinel node biopsy,
  • Axillary clearance
  • Implant breast reconstruction
  • Symmetrising surgery
  • Breast augmentation following breast cancer surgery